![]() ![]() ![]() We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. You should not use the information provided herein to diagnose, prevent, or cure a health problem. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. When the treatment effect on outcome was assessed in pre-specified subgroups, significant interactions were noted for stroke severity and feeding status ( Figure 2).The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. The primary outcome of death and dependency measured using the mRS at day 90 revealed an unfavourable shift to poor outcome in those randomised to continue vs. Variable used in statistical adjustment 2p: 2-sided p-value BP: blood pressure bpm: beats per minute GCS: Glasgow Coma Scale GTN: glyceryl trinitrate IHD: ischaemic heart disease LACS: lacunar syndrome mRS: modified Rankin Scale NIHSS: National Institutes of Health Stroke Scale OTR: time from onset to randomisation PACS: partial anterior circulation syndrome PAD: peripheral artery disease POCS: posterior circulation syndrome SSS: Scandinavian Stroke Scale TIA: transient ischaemic attack TACS: total anterior circulation syndrome upw: units per week. Participants in this target time window of 0), have a feeding status of ‘nothing’, have a higher diastolic BP and be randomised to GTN than no GTN ( Table 1). Of the 4011 participants randomised into ENOS, 2097 were randomised to either stop or continue prior antihypertensive treatment and 384 (18.3% continue 185, stop temporarily 199) of these were recruited within 12 h of symptom onset ( Table 1). In addition, to assess whether baseline imaging markers of small vessel disease and brain frailty Pre-specified subgroup analyses were performed by adding an interaction term to an unadjusted OLR model. Analyses are shown both unadjusted, and adjusted for age, sex, pre-morbid mRS, previous stroke, history of diabetes, prior use of nitrates, final diagnosis, SSS, total anterior circulation syndrome (TACS), SBP, use of thrombolysis, feeding status, time to randomisation, and randomisation to GTN vs. ABBOTT GTN SORBITRATE CR 30S 2.6MG TAB 1 Units / pack. The assumption of proportionality of odds for OLR was tested using the likelihood ratio. Alternatives for MONIT GTN 2.6MG 60S TAB Drugs with same composition & strength. Comparisons between groups used binary logistic regression, Cox proportional hazards regression, ordinal logistic regression (OLR) or multiple linear regression results are given as OR or difference in means (DIM), with 95% confidence intervals (95% CI) and significance, with p<0.05 being considered significant. The Lancet Regional Health – Western Pacificĭata are shown as number (%), median or mean (standard deviation).The Lancet Regional Health – Southeast Asia.The Lancet Gastroenterology & Hepatology. ![]()
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